Preimplantation genetic testing for structural rearrangements (PGT-SR) is a technique used to detect chromosomal structural abnormalities in embryos during in vitro fertilization (IVF). It is applied to couples who carry chromosomal rearrangements, such as translocations, inversions, or deletions, which may increase the risk of miscarriage or genetic disorders. PGT-SR involves analyzing embryos for these structural changes before implantation. By identifying embryos without such abnormalities, it helps increase the chances of a healthy pregnancy. The procedure includes embryo biopsy followed by genetic testing. PGT-SR is particularly beneficial for individuals with known chromosomal rearrangements or a history of pregnancy loss. This testing reduces the risk of passing on structural chromosomal abnormalities to the offspring.