MLPA     (Multiplex     Ligation-dependent      Probe Amplification) is  a   molecular   genetic   technique used to detect gene  deletions,   duplications,   and copy number variations (CNVs) in specific genomic regions. It  is    considered  a   reliable    and    cost-effective   method   for   analyzing   known  genetic alterations. The  assay  uses  validated  probe  sets designed  to  ensure  high  accuracy  and  minimize false results. MLPA is widely used in  the  diagnosis of various inherited genetic disorders.